The World's First Family Centered DNA Bank and Hereditary Information
Service
July, 2000
THE AMERICAN SOCIETY OF CLINICAL ONCOLOGY STRESSES NEED FOR REFERENCE
DNA FOR GENETIC TESTING OF INHERITED DISEASES
(Excerpts reprinted from Diagnostics 2000, Patient Care) "The
American Society of Clinical Oncology (ASCO) has issued guidelines regarding
testing for genetic susceptibility to cancer. ASCO recommends such testing
when 3 conditions are met:
The patient's family has a history of cancer, especially
in cases of early on-set disease.
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The selected test can be interpreted satisfactorily.
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Test results will influence how the patient's cancer risk
is managed.
In deciding whether genetic testing for cancer risk is appropriate,
determine not only whether the patient has a family history of
the disease, but also whether a family member currently has cancer,
as that person should be the first to undergo the test to determine
whether an associated gene mutation is present. If the person with
cancer has a mutation in a cancer predisposition gene, then other
family members may consider testing for that gene mutation. Because
several mutated genes may account for one form of cancer, testing
a family member who has the disease can help identify which gene
is altered. (emphasis added) In a family with a history of
breast cancer, for instance, the first person to be tested should
be someone who already has breast or ovarian cancer. In a family
with a history of colorectal cancer, someone who has colorectal
or possibly endometrial cancer - one of the cancers that may be
included in some of the colorectal syndromes - should be tested
first"
GeneLink maintains that this statement genuinely supports reference
DNA for inherited diseases, and concludes that DNA banking is essential.
If that family member dies before a genetic test can be performed,
surviving family members lose the opportunity to be tested for
inheritance of that disease unless the DNA of the deceased relative
is banked or stored.
GeneLink equips every Funeral Director with the ability to inform
their families of this last chance opportunity to save the DNA
of their loved one for the future benefit of the surviving family
members.
SOURCE:GeneLink BioSciences, Inc.